N.J. man pain-free thanks to sickle cell treatment at CHOP
Black History Month is poignant for one family after a man got a historic, innovative treatment at Children's Hospital of Philadelphia.
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Black History Month is poignant for one family after a man got a historic, innovative treatment at Children's Hospital of Philadelphia.
Austin Louis, 20, says the CRISPR treatment he received at the Children's Hospital of Philadelphia for sickle cell disease changed everything, allowing him to live without pain for the first time.
Baby KJ was successfully treated with a customized CRISPR gene editing therapy by a team at Children's Hospital of Philadelphia and Penn Medicine in a historical medical breakthrough. Now after over 300 days in the hospital, they get to come home.
The CRISPR gene editing therapy has been used for other diseases like sickle cell, but this is the first time it's been customized for one patient.
A first-of-its-kind genetic treatment at Children's Hospital of Philadelphia is restoring and improving vision.
CHOP pioneered a gene therapy that's already helping patients who have sickle cell disease, an inherited blood disorder.
The FDA recently approved the first gene therapies to treat patients with sickle cell disease, an inherited blood disorder. Children's Hospital of Philadelphia helped pioneer the treatment, which experts say is a "real gamechanger" for this disease, which mainly affects people of color.
It won't be quite as warm, and nowhere near as sunny as Saturday, so get the coats back out — along with the umbrella.
Large amounts of water flooded a parking garage at 16th and Callowhill streets in Spring Garden.
After weeks of bitter cold, warmer weather on Valentine's Day drew crowds to Manayunk, giving local restaurants and businesses a boost.
The Fairmount SEPTA station on Broad Street reopens after water was leaking from the ceiling, a transit spokesperson said.
U.S. Olympic gold medalist Breezy Johnson and her fiancé talks about the lead up to their engagement at 2026 Milano Cortina and a congratulations from Taylor Swift.
It won't be quite as warm, and nowhere near as sunny as Saturday, so get the coats back out — along with the umbrella.
Large amounts of water flooded a parking garage at 16th and Callowhill streets in Spring Garden.
After weeks of bitter cold, warmer weather on Valentine's Day drew crowds to Manayunk, giving local restaurants and businesses a boost.
A man has died following a high speed crash in Philadelphia's Torresdale neighborhood in the early hours of Friday morning.
The Fairmount SEPTA station on Broad Street reopens after water was leaking from the ceiling, a transit spokesperson said.
Large amounts of water flooded a parking garage at 16th and Callowhill streets in Spring Garden.
After weeks of bitter cold, warmer weather on Valentine's Day drew crowds to Manayunk, giving local restaurants and businesses a boost.
The Fairmount SEPTA station on Broad Street reopens after water was leaking from the ceiling, a transit spokesperson said.
The Sixers rookie capped off his first apperance at the NBA All-Star weekend with two game-ending scores and an MVP trophy.
Police are investigating a string of late-night robberies in Bella Vista after five assaults over the past month left some victims injured.
After erosion from several major storms, New Jersey officials say federal relief is on the way for eroding South Jersey beaches.
February is Heart Awareness Month, and with Valentine's Day approaching, the holiday holds special meaning for a South Jersey family.
Video from a New Jersey police department's drone helped officers rescue a missing child in dense woods amid severely cold weather.
Quinton Law made history by becoming New Jersey's youngest active serving mayor and Moorestown Township's first Black mayor.
From picking cotton on a Tennessee farm to raising a family in South Jersey, Lillian Crooks is celebrating 100 years of life.
Ice is still impacting bodies of water around the Philadelphia area after a long stretch of cold temperatures.
Two firefighters and two residents were taken to the hospital after a house fire in Wilmington on Sunday, officials said.
Power companies across the Philadelphia region and Lehigh Valley are reporting some outages Saturday while high wind alerts are in effect.
The coldest air of the season is set to slide over the Philadelphia area this weekend, which could lead to frost quakes, ice quakes and lake quakes.
The man whom Jill Biden divorced for the eventual 46th President of the United States is now in jail on murder charges.
February is Heart Awareness Month, and with Valentine's Day approaching, the holiday holds special meaning for a South Jersey family.
As piles of snow melt across the Philadelphia region, research shows the salt used to prevent slipping could end up in the water supply.
Black History Month is poignant for one family after a man got a historic, innovative treatment at Children's Hospital of Philadelphia.
With a measles outbreak in Pennsylvania, local health experts want to send a message to families.
Penn's first successful transplant was a kidney back in 1966. Since then, there have been thousands of life-saving operations.
Move over, Wawa, "there's a new player in town." Customers shed light on Pennsylvania's heated rivalry as Sheetz opened its first store in Montgomery County.
Former Sheetz president and CEO Steve Sheetz has died at age 77, the Altoona-based company announced on Monday.
The post-Christmas return rush was underway at shops and malls across the Philadelphia area.
With product return fraud on the rise, an emerging company is using AI to help spot issues.
Here are mall opening and closing hours for the Christmas and Christmas Eve holidays around the Philly region.
Police and fire crews are once again responding to the scene of a train fire that broke out Thursday.
More than 100 speed bumps near Philadelphia schools were installed improperly, a new report says.
The Downingtown Interchange on the Pennsylvania Turnpike reopened Wednesday night after a canopy over the toll booths collapsed.
A portion of Martin Luther King Jr. Drive remains closed as crews work on water infrastructure repairs.
PennDOT is asking for your input with a new online survey available now through Feb. 28.
U.S. Olympic gold medalist Breezy Johnson and her fiancé talks about the lead up to their engagement at 2026 Milano Cortina and a congratulations from Taylor Swift.
The Sixers rookie capped off his first apperance at the NBA All-Star weekend with two game-ending scores and an MVP trophy.
Olympic organizers promise that the villages where athletes live won't run out of free condoms again during the Milan Cortina Winter Games.
Turns out, the Philadelphia Phillies were ale-ing last year — and it contributed to Nick Castellanos' release.
In his first year as Roman Catholic's head coach, 2007 PCL champion Brad Wanamaker hopes to help Cahillites seniors capture a title.
"Dawson's Creek" and "Varsity Blues" star James Van Der Beek has died at 48 years old.
The Pennsylvania Film Office has awarded $34 million for production on Season 3 of "Tires" and the fifth and final season of "Mayor of Kingstown."
Catherine O'Hara, known for her roles in "Home Alone," "Schitt's Creek" and "Beetlejuice," died on Jan. 30 at the age of 71.
Brad Arnold, the founder and lead singer of the 3 Doors Down has died following "his courageous battle with cancer," the rock band announced Saturday on social media.
Bad Bunny took the stage at halftime for the 2026 Super Bowl. Here's who else performed at Super Bowl 60.
Ukee Washington reports.
Natasha Brown reports.
Natasha Brown reports.
Natasha Brown reports.
Ukee Washington reports.
Middle school students in Philadelphia got the opportunity to do hands-on learning during the school district's five-day career and technical camp.
With her Girl Talk mentoring program, one Philadelphia teen turned her camp days into a safe space to discuss social issues young girls face every day.
Recent high school graduate Sylvain Farrell says his temporary position at a local clinic is the pathway to a full-time career.
A Philadelphia student won an award from NFL Films for his documentary on bringing back sports teams at his Kensington school.
A group of East Norriton eighth graders took what started as an Earth Day project and made a whole initiative.
NEXT Weather Alert has been issued for Sunday evening and night as a large storm system slides past to our south. Bill Kelly has the forecast.
Large amounts of water is flooding a parking garage at 16th and Callowhill streets in Spring Garden. Wakisha Bailey reports.
After a picture perfect date night Saturday, a wintry mix of rain and snow arrives Sunday night. Bill Kelly has the forecast.
Businesses and couples in Philadelphia recieve boost thanks to the warmer weather. Wakisha Bailey reports.
Shops like Stein Your Florist in Mayfair have been nonstop busy, selling flowers, gift baskets and other items. Owner Patrick Kelly says for florists, this is their Super Bowl. Ray Strickland reports.