Health: New Developments In Alzheimer's Research
By Stephanie Stahl
PHILADELPHIA (CBS) -- It is one of the most dreaded diseases of older age: Alzheimer's. Researchers have a good understanding of what causes this most extreme form of dementia, and now, in an exciting development, they are studying a possible way to stop it.
Brain scans show the dreaded amyloid plaques that can cause Alzheimer's disease and now researchers may have a way to stop it, before it robs the mind, and people's lives.
"Amyloid is a protein that our nerve cells produce normally. But in Alzheimer's disease it accumulates into these plaques - plaque build-up," said researcher Reisa Sperling, MD.
Researchers are testing a new drug, known as an anti-amyloid antibody, which can "clear" plaques from the human brain.
Art Canter, who scanned positive for amyloid build-up, is taking part in a clinical trial known as the "A4 Study."
"It's worth it to participate. I have nothing to lose other than the time I'm taking to do an infusion once a month," said Arthur Canter.
Researchers say the idea behind the A4 Study is very similar to what happens with heart disease.
"We find people who have slightly elevated cholesterol and we decrease their cholesterol with statin drugs and hopefully prevent heart attacks and prevent strokes. I think we can do that in Alzheimer's disease," said Sperling.
There's a lot of hope and excitement about this research. The Alzheimer's Association invested $8 million, it's largest grant ever.
People are being enrolled around the country and here in Philadelphia.
Links:
http://www.adcs.org/studies/A4.aspx
