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There's new hope for people with sickle cell disease which affects mainly African Americans. It's gene therapy research at Children's Hospital of Philadelphia that's being called a game changer.
Thousands of Black children with sickle cell disease are struggling to get access to disability payments. According to a public records request shared with CBS News, out of the tens of thousands of families who applied for federal benefits, 76%, more than 12,000 families, had their requests denied between 2015 and 2020. Richard Weishaupt, a lawyer for Community Legal Services, joined CBS News to discuss why all the denials happened.
CHOP pioneered a gene therapy that's already helping patients who have sickle cell disease, an inherited blood disorder.
The Food and Drug Administration on Friday approved the first-ever gene-editing therapy that uses a cutting-edge technology called CRISPR to treat sickle cell disease. Dr. Jon LaPook has more.
The FDA is set to decide Friday on a gene editing technique for patients with sickle cell disease. It would be the first use of CRISPR in the United States to treat a disease. CBS News' chief medical correspondent Dr. Jon LaPook has more.
The Food and Drug Administration is set to vote on the use of gene-editing technology to potentially cure sickle cell disease, the painful genetic blood disorder that affects hundreds of thousands of Black, Hispanic, Asian and Middle Eastern Americans. Dr. Bayo Curry-Winchell, medical director at Saint Mary's Urgent Care Group, joined CBS News to discuss the treatment.
The first gene therapy treatment for sickle cell disease has been approved in the U.K., a move that could offer relief to thousands of people with the disease.
The stopgap measure will fund the government and provide tens of billions in disaster relief.
Police say the driver is under arrest after plowing into the crowd at a Christmas market in Magdeburg, Germany, killing at least five people - including a 9-year-old - and injuring 200 others.
The House Ethics Committee voted to release its report on the investigation into former Rep. Matt Gaetz on Dec. 5, according to multiple sources.
Rickey Henderson is widely considered to be one of the best leadoff hitters and base stealers in baseball.
Mark Burnett helped produce hits like "Survivor" and "The Voice," but is perhaps best known for teaming up with President-elect Donald Trump for "The Apprentice," which first aired in 2004.
An F/A-18 fighter jet was "mistakenly fired on" by the guided missile cruiser USS Gettysburg, authorities said.
Kari Lake, a former broadcast journalist who unsuccessfully ran for governor and for a U.S. Senate seat in Arizona, is President-elect Donald Trump's selection to lead Voice of America.
The suspect drove through the doors of a JC Penny in Killeen, Texas, and continued inside for "several hundred yards," an official said.
Party City informed employees in an email on Friday that it was conducting an immediate "mass layoff" at its headquarters.
Kari Lake, a former broadcast journalist who unsuccessfully ran for governor and for a U.S. Senate seat in Arizona, is President-elect Donald Trump's selection to lead Voice of America.
A look back at how "48 Hours" covered the 1996 Christmastime murder of JonBenét Ramsey in 2002, and what her father John Ramsey says about the unsolved Colorado case nearly 28 years later.
Lara Trump, the daughter-in-law of President-elect Donald Trump, says she's removing herself from consideration for Marco Rubio's Senate seat.
After California man's death sentence is overturned, there's a renewed push to clear him.
The suspect drove through the doors of a JCPenny in Killeen, Texas, and continued inside for "several hundred yards," an official said.
Party City informed employees in an email on Friday that it was conducting an immediate "mass layoff" at its headquarters.
Senators approve a bill to expand Social Security benefits to millions of Americans, with President Biden expected to sign it into law.
Here's what's driving up home heating costs, and how much families are expected to spend this winter.
The IRS said it's sending out checks worth up to $1,400 to 1 million people. Here's what to know about the "special payments."
Government watchdog claims Americans lost hundreds of millions to fraud related to the bank-operated mobile payments network.
Kari Lake, a former broadcast journalist who unsuccessfully ran for governor and for a U.S. Senate seat in Arizona, is President-elect Donald Trump's selection to lead Voice of America.
Lara Trump, the daughter-in-law of President-elect Donald Trump, says she's removing herself from consideration for Marco Rubio's Senate seat.
An F/A-18 fighter jet was "mistakenly fired on" by the guided missile cruiser USS Gettysburg, authorities said.
Mark Burnett helped produce hits like "Survivor" and "The Voice," but is perhaps best known for teaming up with President-elect Donald Trump for "The Apprentice," which first aired in 2004.
The Senate confirmed two more judges to the federal bench on Friday, giving President Biden a total of 235 since he took office.
Thirteen states reported "high" or "very high" levels of flu-like illness last week, according to the U.S. Centers for Disease Control and Prevention. That's double the number of states from the week before. Ali Bauman reports.
Isaac Klapper was 10 years old when he started having episodes of what doctors initially thought was a movement disorder.
Humans aren't alone when it comes to yawning — all vertebrates do it. But why? An expert explains the likely reason behind this "evolutionarily ancient" act.
Skin care is all the rage for teens and tweens these days, but be careful not to give products that could cause more harm than good.
A Chicago man was stuck with a big medical bill after undergoing a colonoscopy that found no evidence of cancer. Here's why.
An F/A-18 fighter jet was "mistakenly fired on" by the guided missile cruiser USS Gettysburg, authorities said.
Pope Francis has told Vatican bureaucrats to stop speaking ill of one another, calling gossip "an evil that destroys social life."
In 2024, more than 10,000 people died in traffic accidents in Brazil, according to the Ministry of Transportation.
Inside Gaza, mourners held funerals for 19 people, 12 of them children, killed in Israeli strikes.
The suspect, identified by local media as 50-year-old Taleb A., was arrested after plowing a black BMW into a Christmas market crowded with holiday shoppers in Magdeburg, Germany, killing at least five people and wounding more than 200 others.
Hollywood star Blake Lively is accusing her "It Ends With Us" co-star Justin Baldoni of sexual harassment in a new lawsuit. His attorney has denied the allegations.
The lawsuit lays out Blake Lively's allegations against Justin Baldoni during their time working on "It Ends with Us."
The New York City Ballet has been performing "The Nutcracker" for decades. Each year, young dancers make their mark on the ballet.
Director Robert Eggers' highly-anticipated horror film "Nosferatu" will hit theaters on Christmas Day. The acclaimed director sat down with CBS Saturday Morning to talk about bringing the classic vampire tale to a new audience.
50 years ago, "The Godfather Part II" was playing in theaters nationwide. The film catapulted Lee Strasberg, whose namesake form of acting preparation was used by some of the film's leads, to stardom. Dozens of the entertainment industry's biggest stars have trained at his institute, learning the techniques of method acting. Michelle Miller went behind the scenes to learn more about "The Method Man."
The Supreme Court said Wednesday it will hear an appeal from TikTok over a federal law that would ban the social media giant if it is not sold by its Chinese parent company. Jan Crawford has more.
Elliston Berry's life was turned upside down after a photo she posted on Instagram was digitally altered online to be pornographic.
From labor shortages to environmental impacts, farmers are looking to AI to help revolutionize the agriculture industry. One California startup, Farm-ng, is tapping into the power of AI and robotics to perform a wide range of tasks, including seeding, weeding and harvesting.
The Supreme Court plans to hear arguments in January on a challenge to a new law that could lead to the popular social media app TikTok being banned in the U.S. The Biden administration and lawmakers say the Chinese government's ability to collect data from TikTok poses a significant national security risk, while the app and its Chinese parent company ByteDance argue that the law is unconstitutional. CBS News Supreme Court producer Catherine Cole has more.
FAA data shows that lithium battery fires on U.S. flights have risen 388% since 2015, now occurring nearly twice a week.
The 2024 winter solstice, the shortest day of the year, happens on Saturday, Dec. 21, and is marked with traditions and celebrations around the world.
This week a group of plaintiffs in Missouri, Kansas, California and Florida filed a class-action lawsuit against dozens of companies and organizations, claiming they've falsely promoted how easy it is to recycle plastics. CBS News Los Angeles climatologist Marina Jurica has the details.
Humans aren't alone when it comes to yawning — all vertebrates do it. But why? An expert explains the likely reason behind this "evolutionarily ancient" act.
Early Americans may have spent millennia sharing prehistoric savannas and wetlands with enormous beasts, research shows.
The Environmental Protection Agency under President Biden created a new Office of Environmental Justice that seeks to address pollution levels in disadvantaged and marginalized communities. However, there is concern that the incoming Trump administration could do away with the new department. David Schechter reports.
A look back at how "48 Hours" covered the 1996 Christmastime murder of JonBenét Ramsey in 2002, and what her father John Ramsey says about the unsolved Colorado case nearly 28 years later.
After California man's death sentence is overturned, there's a renewed push to clear him.
The suspect drove through the doors of a JCPenny in Killeen, Texas, and continued inside for "several hundred yards," an official said.
Luigi Mangione, now held in a New York City lock-up, could face the death penalty if convicted of the shooting death of UnitedHealthcare CEO Brian Thompson. The killing is sparking new concerns about violent extremism bubbling across the country.
At least two people are dead and dozens more injured after a vehicle plowed into a crowd at a Christmas market in Magdeburg, Germany. Authorities say the driver of the car was arrested and that it appears to be a deliberate attack. Elaine Cobbe has details.
New analysis techniques and decades-old research helped NASA scientists identify an unusual black hole in a distant galaxy.
Here's why NASA astronauts Suni Williams and Butch Wilmore are stuck, but not stranded, at the International Space Station after launching into space in June.
NASA has delayed the return date for Boeing's Starliner astronauts Butch Wilmore and Suni Williams. CBS News' Manuel Bojorquez reports on the decision to keep the two in space.
NASA Administrator Bill Nelson says he's optimistic the Trump administration will support the space agency's agenda.
Two astronauts who have been stuck in space since June will have to wait until at least the end of March to come home after NASA on Wednesday again pushed back their return date. Derrick Pitts, chief astronomer for the Franklin Institute, joined CBS News to discuss what's causing the delays.
A look back at the esteemed personalities who've left us this year, who'd touched us with their innovation, creativity and humanity.
Peterson's death sentence for the murder of his pregnant wife Laci has been overturned. Now his supporters are pushing for a complete retrial.
The seesaw marriage between the former ballerina and her much older husband only lasted four years, until she shot him on Sept. 27, 2020.
Cayley Mandadi's mother and stepfather go to extreme lengths to prove her death was no accident.
Live performances are in full swing this summer. Scroll through our concert gallery, featuring pictures by CBS News photojournalist Jake Barlow and photographers Ed Spinelli and Kirstine Walton.
Is there new hope to solve the murder of JonBenét Ramsey? Her father says there’s a way. "48 Hours" correspondent Erin Moriarty reports.
Here's a look at the top stories making headlines on the "CBS Weekend News" with David Wade.
Many kids will be getting tablets or video games this holiday season. But this Boston boy has put down the gadgets and lifted up his entire neighborhood. David Wade reports.
The Chicago group Holiday Heroes seeks to bring joy and light to brave children at 18 different hospitals. Noel Brennan has more.
Hollywood star Blake Lively is accusing her "It Ends With Us" co-star Justin Baldoni of sexual harassment in a new lawsuit. His attorney has denied the allegations.