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49ers Week 11 Injury Report: Defense Still Wounded As Brady And Patriots Come Calling

Few defenses embrace the challenge of facing quarterback Tom Brady and the New England Patriots offense, especially when injuries have depleted the starting lineup and the backup units. But that's the case for the San Francisco 49ers this weekend as they host the Pats at Levi's Stadium in Santa Clara. The 49ers have the worst defense in the NFL, and with several defensive players still injured and on the mend, it's not the best time to face Brady and all his offensive weapons.

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