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Like most girls her age, 11-year-old Luna Duffy is a big Taylor Swift fan and has learned how to play some of Swift's songs on the piano.
During the summer of 2021, Elizabeth Loughren of Oakmont was like any other 10-year-old girl, until she wasn't.
Sickle cell disease affects approximately 100,000 people in the U.S., predominantly people of color.
An estimated one in eight women will develop breast cancer in their lifetime, killing on average 42,000 a year in the U.S. But what if a vaccine could significantly lower each woman's chance of ever getting it in the first place?
Pediatricians are seeing an increase in pediatric cases of respiratory viral infections and the flu, Allegheny Health Network says.
With all the food, drink, candy, and parties, it's easy to let go during the holidays, but it is avoidable while still enjoying it.
Casual dining chain faces another wrongful death suit related to its Charged Lemonade after cardiac arrest of Florida man.
The American Academy of Pediatrics is sounding the alarm on excessive noise that kids and teens are exposed to.
State Rep. Arvind Venkat's bills would help promote food safety at restaurants across the commonwealth.
It's the time of year when the trees go up, the lights get lit, and sadly, people get hurt.
Clementine Blackham needed a rare, life-saving bone marrow transplant which she eventually received.
The "Charmed" and "Beverly Hills, 90210" actor said she hopes to get into clinical trials as new treatments are developed but what drives her now is the desire "to prove" that she can work despite her cancer diagnosis.
The tests will be available from a federal stockpile starting in December, and schools can distribute them to students, families, staff and larger school communities.
Recalled Burn Boot Camp snacks were sold at locations run by gym franchises throughout the U.S.
FDA finds reasonable expectation of effectiveness for drug designed to keep bigger breeds around longer, biotech firm says.
A man was taken to the hospital after he was stabbed in the stomach late on Friday night.
One person was killed in a house fire in Braddock on Friday night.
More than 90,000 customers are under a boil water notice due to an early morning power surge at a treatment plant.
Temperatures will be in the single digits and below zero with wind chills in the Pittsburgh area.
Actor Michael Keaton was roasted before receiving the 2026 Man of the Year by Harvard University's Hasty Pudding Theatricals.
The footage is included in a video that promotes false claims that the 2020 presidential election was rigged against Mr. Trump.
The bipartisan "Bell-to-Bell" bill bars students from using their phones any time they're in school, not just during instructional periods.
It was only a few months ago that Pennsylvania passed the 2025 budget several months late, and now the process begins for this year.
Pennsylvania Gov. Shapiro delivered his fourth budget address at the State Capitol in Harrisburg, three months after last year's budget was passed by state lawmakers.
A federal judge on Monday blocked the Trump administration from revoking Temporary Protected Status for Haitians, granting a last-minute reprieve to 350,000 immigrants who were set to lose protections on Tuesday.
More than 90,000 customers are under a boil water notice due to an early morning power surge at a treatment plant.
A woman and her husband are fighting for a $400 refund after they bought furniture from a Value City Furniture store.
It's the end of an era for a grocery store in Carrick.
A Pennsylvania couple says Kia wrongly denied a warranty claim after their car's engine failed at 80,000 miles.
Scams targeting utility customers are on the rise in Pennsylvania, the attorney general says.
Daisy takes us live to learn more about 100.7 Star's Best Pizza in Pittsburgh competition.
We’re hearing from some of you! How did you meet? What is your love story?
Daisy shows us how to see our closet in a different way.
Some local pups will be in the game this year, and we’re meeting one from Animal Friends!
The band has a Pittsburgh connection, and we’re getting a performance live in the studio!
Residents of Millvale are trying to get back to normal after last weekend's major snowstorm.
Tracing the past of Shane Hennen and how his troubled life in Pittsburgh pointed to his future downfall.
People in Avella, Washington County, say they have no phone coverage.
Residents and leaders in Charleroi are concerned about the integrity of roads after a trench collapse last year and ongoing construction.
Patrick Vereb is accused of taking money from pet owners who believed their animals would receive dignified cremations.
More than 90,000 customers are under a boil water notice due to an early morning power surge at a treatment plant.
Doctors said the drugs can help people lose unwanted pounds while retaining muscle.
Southwestern Pennsylvania's cold and snowy winter is taking its toll on more than just our roadways and walkways.
The Liberty-Clairton area is under a code orange air quality action day, according to the Pa. Dept. of Environmental Protection.
The cold weather and lingering snow affect more than just the roads and our cars, it affects our brains.
Prosecutors have dropped the most serious assault charge against Penn State hockey star Gavin McKenna.
Western Pennsylvania has historically been a hotbed for producing talent that succeeds in the NFL.
A person familiar with the negotiations tells The Associated Press that pitcher José Urquidy and the Pittsburgh Pirates have agreed to a $1.5 million, one-year contract.
Wide receiver Larry Fitzgerald headlines the five-player 2026 Pro Football Hall of Fame class.
The Pittsburgh Penguins beat the Buffalo Sabres 5-2 on Thursday night in the final game for both teams before the Olympic break.
More than 140 employees at Nemacolin were informed they were being let go.
It's been about six years since the pandemic, and a lot of people working from home, but now companies are slowly calling them back to the office.
Pittsburgh Mayor Corey O'Connor on Tuesday announced a new initiative aimed at revitalizing neighborhood business districts across the city.
A handful of Pittsburgh-area Value City Furniture stores are going out of business after their parent company filed for bankruptcy.
It has been five years since the home improvement retailer Menards bought a large parcel of land off Route 30 in Westmoreland County.
Filming for the final season of "Mayor of Kingstown" is expected to take place between March and June.
Many Super Bowl 60 ads are already online, along with teasers for commercials that will be unveiled during the NFL championship on Feb. 8.
"Stick Season" singer Noah Kahan is coming to Pittsburgh this summer.
Music's biggest night returned Sunday with the 68th annual Grammy Awards. Here is how to watch and stream and what to know.
Catherine O'Hara was best known for her comic performances in projects including "Home Alone," "Beetlejuice," and "Schitt's Creek."
A man is in stable condition after he was stabbed in the abdomen late on Friday night.
One person was killed and a firefighter had to be treated at the scene of a house fire in Braddock on Friday night.
Stay on top of local weather with meteorologist Mary Ours’s forecast!
KDKA-TV Sports' Cassidy Wood and the Post-Gazette's Jason Mackey discuss the sports topics of the day.
Chuck Dorgan was one of the 20-plus vehicles involved in the crash. He said the scariest moment wasn't when he crashed his truck. It was what happened after.
Mike Tomlin stepped down as head coach of the Pittsburgh Steelers after 19 seasons with the team.
Pitt's regular season has ended with an 8-4 record.
Pitt's five-game winning streak came to an end with a 37-15 loss to Notre Dame.
Mason Heintschel set a new Pitt freshman single-game passing record in the Pitt win at Acrisure Stadium.
The 44th annual KDKA-TV Turkey Fund will help our neighbors in need have a nice meal for Thanksgiving.
