CBS/Sheryl Nields
Julia Louis-Dreyfus stars as Christine Campbell on CBS' "The New Adventures of Old Christine." "Christine" has been canceled after five seasons on the air.
ABC/Bob D'Amico
Lost will end after six seasons when its series finale airs on May 23, 2010. The show's large ensemble includes Matthew Fox, Evangeline Lily, Josh Holloway and Emmy-winner Michael Emerson.
FOX/Brian Bowen Smith
Kiefer Sutherland as Jack Bauer on "24." Fox has canceled the drama after eight seasons, but Sutherland isn't done playing Bauer just yet - a feature film based on the show is in the works.
ABC
Joseph Fiennes as Agent Mark Benford on "FlashForward." ABC has canceled the drama after just one season.
FOX/Sam Jones
Brad Garrett, left, and Joely Fisher in Fox's "'Til Death." The network has canceled the show, which aired for four seasons.
CBS/Art Streiber
Jenna Elfman stars as Billie on the CBS comedy "Accidentally on Purpose." The show was canceled after its first and only season.
AP Photo/ABC, Patrick Harbron
America Ferrera portrays Betty Suarez in a scene from the series finale of "Ugly Betty," airing Wednesday, April 14, 2010. The ABC comedy came to an end after four seasons.
AP Photo/Katy Winn
Alyssa Milano's ABC comedy "Romantically Challenged" premiered on April 19, 2010, and was canceled on May 16.
AP
Portia De Rossi's ABC comedy "Better Off Ted" was canceled after two seasons.
AP Photo/Peter Kramer
Zach Braff will no longer have to don his "Scrubs" - the show has been canceled after seven seasons on NBC and two others on ABC.
AP Photo
Christian Slater's drama "The Forgotten" was canceled by ABC after one season.