Out of Work in Hollywood

Jennifer Love Hewitt is seen as Melinda Gordon on CBS' "Ghost Whisperer." The series has been canceled after five seasons.

CBS Cuts "Ghost Whisperer"

The cast of NBC's "Law & Order." NBC canceled the drama after 20 seasons on the air.

Pictures: Sam Waterston
Pictures: Favorite Crime TV Shows

Julia Louis-Dreyfus stars as Christine Campbell on CBS' "The New Adventures of Old Christine." "Christine" has been canceled after five seasons on the air.

Pictures: Julia Louis-Dreyfus

Lost will end after six seasons when its series finale airs on May 23, 2010. The show's large ensemble includes Matthew Fox, Evangeline Lily, Josh Holloway and Emmy-winner Michael Emerson.

Kiefer Sutherland as Jack Bauer on "24." Fox has canceled the drama after eight seasons, but Sutherland isn't done playing Bauer just yet - a feature film based on the show is in the works.

Joseph Fiennes as Agent Mark Benford on "FlashForward." ABC has canceled the drama after just one season.

Brad Garrett, left, and Joely Fisher in Fox's "'Til Death." The network has canceled the show, which aired for four seasons.

Jenna Elfman stars as Billie on the CBS comedy "Accidentally on Purpose." The show was canceled after its first and only season.

America Ferrera portrays Betty Suarez in a scene from the series finale of "Ugly Betty," airing Wednesday, April 14, 2010. The ABC comedy came to an end after four seasons.

Pictures: America Ferrera

Michelle Trachtenberg as Chloe Payne on NBC's "Mercy," which was canceled during its first season.

NBC canceled its drama "Heroes" after four seasons. The show's ensemble cast included Hayden Panettiere, Milo Ventimiglia and Zachary Quinto.

Even Heather Locklear couldn't save the revamp of "Melrose Place" -- the CW drama was canceled during its first season.

Pictures: Heather Locklear

Alyssa Milano's ABC comedy "Romantically Challenged" premiered on April 19, 2010, and was canceled on May 16.

Portia De Rossi's ABC comedy "Better Off Ted" was canceled after two seasons.

Zach Braff will no longer have to don his "Scrubs" - the show has been canceled after seven seasons on NBC and two others on ABC.

Christian Slater's drama "The Forgotten" was canceled by ABC after one season.