President-elect John F. Kennedy, left, shakes hands with Vice President Richard M. Nixon after a post-election conference in Miami, Nov. 14, 1960. Nixon lost to Kennedy in the election.
President Kennedy and first lady Jacqueline Kennedy pose at Georgetown University Hospital in Washington, Dec. 8, 1960, with their son, John F. Kennedy Jr., following a baptism for the infant. The younger Kennedy was born Nov. 25.
Chief Justice Earl Warren administers oath of office to President John F. Kennedy in Washington, D.C., Jan. 20, 1961. Vice President Lyndon B. Johnson is at right. Holding the Bible at center is James R. Browning, clerk of the U.S. Supreme Court. Richard M. Nixon stands at far right.
After taking the oath of office, U.S. President John F. Kennedy delivers his inaugural address at Capitol Hill in Washington, D.C., Jan. 20, 1961. Kennedy said, "We shall pay any price, bear any burden, meet any hardship, support any friend, oppose any foe, to assure the survival and success of liberty."
President John F. Kennedy is shown with Frank Sinatra at the Inaugural Ball in Washington, D.C., Jan. 20, 1961.
With their heads bowed, President John F. Kennedy, left, walks along a path at Camp David near Thurmond, Md., with former President Dwight D. Eisenhower, April 22, 1961. The two met to discuss the Bay of Pigs invasion.
Widely grinning President John F. Kennedy, right, looks up toward comedian Bob Hope in New York's Waldorf-Astoria Hotel, May 30, 1961. The President was principal speaker at the Salute to General Omar N. Bradley and the First Annual World Peace Through World Health dinner of the Eleanor Roosevelt Cancer Foundation.
U.S. First Lady Jacqueline Kennedy, wearing an Oleg Cassini gown, is with President John F. Kennedy in Paris, France, May 31, 1961.
Soviet Premier Nikita Khrushchev, left, and U.S. President John F. Kennedy sit in the residence of the U.S. ambassador in Vienna, Austria, at the start of their historic talks, June 3, 1961.
U.S. President John F. Kennedy addresses the United Nations General Assembly in New York, Sept. 25, 1961. President Kennedy tells the U.N. delegates the United States has "both the will and the weapons" to resist aggression.
Mercury astronaut John Glenn shows the Friendship 7 Space Capsule to President John F. Kennedy and Vice President Lyndon Johnson in Cape Canaveral, Fla., Feb. 23, 1962.
U.S. President John F. Kennedy, left foreground, meets with Soviet Foreign Minister Andrei Gromyko, right foreground, and U.S. Ambassador to Russia Llewellyn Thompson, center, during the Cuban Missile Crisis.
U.S. President John F. Kennedy, right, confers with his brother Attorney General Robert F. Kennedy at the White House in Washington, D.C., Oct. 1, 1962, during the buildup of military tensions between the U.S. and the Soviet Union that became the Cuban missile crisis.
President John F. Kennedy makes a national television speech Oct. 22, 1962, from Washington. He announced a naval blockade of Cuba until Soviet missiles are removed.
President Kennedy claps time as his children Caroline, who would turn 5 years old on Nov. 17, and John Jr., who would be 2 on Nov. 25, dance in the President's White House office, October 1962.
President John F. Kennedy and family pose outside the Palm Beach, Fla., home of the president's father after a private Easter Service, April 14, 1963. From left are first lady Jacqueline Kennedy; John Jr., 3; President Kennedy; and Caroline, 5.
Boy's Nation delegate Bill Clinton, left, shakes hands with President John F. Kennedy, June 6, 1963.
U.S. President John F. Kennedy is greeted by an enthusiastic crowd of children and nuns from the Convent of Mercy, as he arrives from Dublin by helicopter at Galway's sports ground, Ireland, June 29, 1963.
Jacqueline Kennedy and U.S. President John F. Kennedy are shown in the backseat of a car as they leave Otis Air Force Base Hospital, Mass., Aug. 14, 1963. One week earlier, the first lady gave birth to their premature son, Patrick Bouvier Kennedy, who died two days later.
President Kennedy, working late at his White House office, wears a slight smile on his face, indicating perhaps he is not completely unaware that his son, John Jr., is exploring under his desk in the Oval Office in the White House in 1963.