Jane Kaczmarek

Jane Kaczmarek attends the ABC Television Network Upfront at Lincoln Center in New York on May 16, 2006. She has recently been nominated for an Outstanding Lead Actress In A Comedy Series Emmy for her work on Fox's "Malcolm in the Middle."

Actor/Event hosts Bradley Whitford and his wife, Jane Kaczmarek, attend In Style & Saturn 2006 Awards Season Benefit For Clothes Off Our Back at Venue at the Republic in Los Angeles on March 9, 2006. The couple, who are very active when it comes to charity, live in L.A. with their three children.

Jane Kaczmarek and Bryan Cranston, who play husband and wife on "Malcolm in the Middle," attend the Fox Winter TCA Party at Citizen Smith in Hollywood on Jan. 17, 2006. The show aired its series finale on May 2006. Kaczmarek is the most decorated cast member on the show, earning three Golden Globe Nominations and seven Emmy nominations (one for every year Malcolm has been on).

TV personality Paula Zahn and actors Michael J. Fox, and Jane Kaczmarek attend the AARP Magazine 2006 IMPACT Awards in New York on Dec. 5, 2005. Throughout her career, Kaczmarek has had recurring roles on "Felicity," "Party of Five," "Frasier," "The Practice," "Cybill" and "Hill Street Blues." She has also voiced a "Simpsons" character, Judge Constance Harm.

Jane Kaczmarek poses with a pair of ruby red slippers that she designed for the screening of "The Wizard of Oz," marking the movie classic's 50th anniversary at the Academy of Motion Picture Arts and Sciences Samuel Goldwyn Theatre in Beverly Hills, Calif., on Oct. 19, 2005. Kaczmarek has appeared in several movies, including the 1998 film "Pleasantville," in which she played Tobey Maguire and Reese Witherspoon's mother.

Jane Kaczmarek, left, and Cheryl Hines, who stars on HBO's "Curb Your Enthusiasm," attend a reception for Emmy Award nominees at Spago in Beverly Hills, Calif., on Sept. 18, 2003. Kaczmarek, who has been nominated for seven Emmys, has yet to win one.

Jane Kaczmarek holds her best actress award during taping of the Third Annual Family Awards in Beverly Hills, Calif., on Aug. 2, 2001. Before landing her role on "Malcolm in the Middle," she appeared in several Broadway hits, including "Lost In Yonkers" and "Raised In Capativity."

Jane Kaczmarek poses with her award for Funniest Female Performer In A Television Series at the 15th Annual American Comedy Awards in Los Angeles on April 22, 2001. The actress was college buddies with "Monk" star Tony Shalhoub.