Forbes' Most Powerful Women 2010

First lady Michelle Obama topped the 2010 Forbes' Most Powerful Women list. According to Forbes, the annual list is "based less on traditional calculations of wealth and executive position, and more on creative influence and entrepreneurship."

Photos: Michelle Obama: First Lady
Michelle Obama Tops Forbes' Powerful Women List

Actress and talk show host Ellen DeGeneres ranked 10th on the 2010 Forbes' List of Most Powerful Women. Here she is seen at the unveiling of the US Postal Service Animal Rescue: Adopt a Shelter Pet Stamps in Los Angeles on April 30, 2010.

Photos: Ellen DeGeneres
Michelle Obama Tops Forbes' Powerful Women List

Queen Rania Al Abdullah of Jordan, ranked number 75 on the Forbes' list, speaks at the annual Clinton Global Initiative on Wednesday, Sept. 22, 2010, in New York.

Photos: Queen Rania of Jordan
Michelle Obama Tops Forbes' Powerful Women List

Talk show host and author Chelsea Handler came in at number 33 on the this year's Forbes' List of Most Powerful Women. In this photo, she arrives at the 2009 Women In Film Crystal and Lucy Awards on June 12, 2009 in Century City, Calif.

Michelle Obama Tops Forbes' Powerful Women List

Pop star Lady Gaga is listed at number seven on the 2010 Forbes' List of Most Powerful Women. Here, the "Poker Face" singer is seen in the press room during the 2010 MTV Video Music Awards, Sept. 12, 2010, in Los Angeles.

Photos: Lady Gaga
Michelle Obama Tops Forbes' Powerful Women List

Former Alaska governor Sarah Palin earned her spot on the 2010 Forbes' List of Most Powerful Women at number 16. Here she is seen at Glenn Beck's "Restoring Honor" rally in Washington, Aug. 28, 2010.

Michelle Obama Tops Forbes' Powerful Women List

Media mogul Oprah Winfrey, who recently kicked off the final season of her syndicated talk show, made the top five at number three on the 2010 Forbes' List of the Most Powerful Women.

Photos: Oprah Winfrey
Michelle Obama Tops Forbes' Powerful Women List

Stephenie Meyer, author of the hit "Twilight" series, was ranked 49 on the Forbes' Most Powerful Women of this year. Here she is seen at the premiere of "The Twilight Saga: Eclipse" at the Nokia Theater in Los Angeles, June 24. 2010.

Michelle Obama Tops Forbes' Powerful Women List

U.S. Secretary of State Hilary Rodham Clinton ranked number five on the 2010 Forbes' Most Powerful Women list. Here she speaks during an event at the State Department on Oct. 7, 2010, in Washington.

Michelle Obama Tops Forbes' Powerful Women List

Supreme Court Justice Ruth Bader Ginsburg poses during a group photograph at the Supreme Court building on Sept. 29, 2009, in Washington. She came in at number 31 on the Forbes 2010 List of Most Powerful Women.

Michelle Obama Tops Forbes' Powerful Women List

Actress and U.N. Ambassador Angelina Jolie came in number 21 on this years Forbes' Most Powerful Women list. Here she is seen at the London premiere of her film "Salt" on Aug. 16, 2010.

Pictures: Angelina Jolie
Michelle Obama Tops Forbes' Powerful Women List

Vogue Editor Anna Wintour attends the 45th annual National Magazine Awards in New York on Thursday, April 22, 2010. She ranked 56 on this years Forbes' list.

Photos: Anna Wintour
Michelle Obama Tops Forbes' Powerful Women List

Talk show host Rachel Maddow made this year's Forbes' Most Powerful Women list at number 50. Here she is seen at the 2009 Winter Television Critics Association Press Tour on Jan. 15, 2009, in Los Angeles.

Michelle Obama Tops Forbes' Powerful Women List

The first lady of France, Carla Bruni-Sarkozy, made the 2010 Forbes' List of Most Powerful Women at number 35.

Photos: Carla Bruni-Sarkozy
Michelle Obama Tops Forbes' Powerful Women List

Gareth Cattermole/Getty Images for Burberry

Actress and fashion designer Sarah Jessica Parker attends the Burberry Prorsum Spring/Summer 2011 fashion show during London Fashion Week, Sept. 21, 2010, in London. The former "Sex and the City" star was recognized on the 2010 Forbes' List of Most Powerful Women at 45.

Michelle Obama Tops Forbes' Powerful Women List

The Supreme Court's newest Justice Elena Kagan smiles after being sworn in by Chief Justice John Roberts at the Supreme Court Building, Aug.7, 2010, in Washington. She is listed as number 25 on the 2010 Forbes' List of Most Powerful Women.

Photos: Elena Kagan
Michelle Obama Tops Forbes' Powerful Women List

Tennis star Serena Williams, ranked at number 55 on the Forbes' list of Most Powerful Women, attends "Fashion's Night Out: The Show" at Lincoln Center in New York, Sept. 7, 2010. Her older sister, Venus Williams, also made this years list, coming in at number 60.

Michelle Obama Tops Forbes' Powerful Women List

CBS news anchor Katie Couric speaks during the Clinton Global Initiative, Tuesday, Sept. 21, 2010, in New York. She came in number 22 on the 2010 Forbes' list of Most Powerful Women.

Photos: Katie Couric
Michelle Obama Tops Forbes' Powerful Women List

Beyonce Knowles poses for pictures at a press conference on June 22, 2009, in New York. The Grammy-winning singer and fashion designer made this year's Forbes' Most Powerful Women List at number 9.

Photos: Beyonce
Michelle Obama Tops Forbes' Powerful Women List

Huffington Post founder and editor-in-chief, Arianna Huffington, arrives at the Time 100 gala,May 8, 2007,in New York. She was listed as number 28 on this year's Forbes' List of Most Powerful Women.

Michelle Obama Tops Forbes' Powerful Women List

Supermodel and "Project Runway" host Heidi Klum takes her spot on the Forbes' List of Most Powerful Women this year at number 39. Here she is seen walking the catwalk during the Victoria's Secret Fashion Show, Nov. 19, 2009, in New York.

Michelle Obama Tops Forbes' Powerful Women List

Gisele Bundchen in 2005. — Getty Images/Carlos Alvarez

Gisele Bundchen is the second supermodel to make it on this year's Forbes' Most Powerful Women list. The Brazilian beauty is also ranked number 1 on Forbes' list of the world's highest paid models for 2010.

Photos: Gisele Bundchen
Michelle Obama Tops Forbes' Powerful Women List

Madonna performs at "Hope for Haiti Now: A Global Benefit for Earthquake Relief", on Friday, Jan. 22, 2010, in New York. The singer and fashion designer ranked number 29 on the 2010 Forbes' List of Most Powerful Women.

Photos: Madonna
Michelle Obama Tops Forbes' Powerful Women List

Talk show host and author Rachael Ray ranked at number 78 on this year's Forbes' Most Powerful Women list. Here she is seen walking the redcarpet at the US Weekly's 25 Most Stylish New Yorkers event on Sept. 15, 2010, in New York.

Michelle Obama Tops Forbes' Powerful Women List

Michael Buckner/Getty Images for Mercedes-Benz

With the help of her signature line of clothing and accessories, fashion designer Tory Burch comes in number 88 on the 2010 Forbes' List of Most Powerful Women.

Michelle Obama Tops Forbes' Powerful Women List

Lifestyle guru and talk show host Martha Stewart earned her spot on the 2010 Forbes' List of Most Powerful Women at number 99. Here she attends the Showtime screening of "The Big C" at the private home of Donna Karan on Aug. 7, 2010, in East Hampton, New York.

Michelle Obama Tops Forbes' Powerful Women List