David Arquette & Courteney Cox

Courteney Cox and David Arquette announced on Oct. 11, 2010, they have been separated for some time but said they remain committed parents and "best friends." The actors released a joint statement announcing what they are calling a trial separation. Cox, 46, and Arquette, 39, met on the set of the film "Scream" in 1996 and married three years later. They have a 6-year-old daughter, Coco.

Courteney Cox and husband David Arquette pose together at the 2010 Crystal Lucy Awards to support Women in Film, held at the Hyatt Regency Century Plaza Hotel in Los Angeles, Tuesday, June 1, 2010. Cox was one of the award winners.

Photos: Courteney's Cause

From left, actor-director David Arquette, his wife actress Courteney Cox; his sister, actress Patricia Arquette, and her husband, Thomas Jane pose together as they arrive at the "Rock a Little, Feed a Lot" concert on Tuesday, Sept. 29, 2009, in Los Angeles.

Courteney Cox and David Arquette arrive at the 67th Annual Golden Globe Awards on Sunday, Jan. 17, 2010, in Beverly Hills, Calif.

Actors Courteney Cox, left, and David Arquette arrive at A Time For Heroes celebrity carnival Sunday, June 8, 2008, in Los Angeles. The carnival event was sponsored by Disney to benefit the Elizabeth Glaser Pediatric Aids Foundation.

Courteney and David — AP Photo/Matt Sayles

David Arquette, right, and Courteney Cox arrive at the Finding Nemo Submarine Voyage Celebrity Preview at Disneyland Park in Anaheim, Calif., on Sunday, June 10, 2007.

David Arquette, left, and Courteney Cox arrive at the premiere of "The Tripper" in Los Angeles on Wednesday, April 11, 2007. The film was written and directed by Arquette.

Jennifer Aniston, left, David Arquette, center, and Courteney Cox speak to each other at the premiere of "The Tripper" in Los Angeles on Wednesday, April 11, 2007.

Actors David Arquette and Courteney Cox arrive at the premiere of the FX Network's "The Riches" at the Zanuck Theater on the Fox Studio lot on March 10, 2007, in Los Angeles.

Courteney Cox and David Arquette present the award for Best Television Series Drama onstage during the 64th Annual Golden Globe Awards at the Beverly Hilton on Jan. 15, 2007, in Beverly Hills, Calif.

David Arquette (left) and actress Courteney Cox arrives at the premiere of the — Charley Gallay/Getty Images

Actor David Arquette and actress Courteney Cox arrive at the premiere screening of the FX Network's "Dirt" at the Paramount Theater on Dec. 9, 2006, in Los Angeles.

Actress Courteney Cox, right, and her husband, actor David Arquette, pose for photographers at the "A Night at the Comedy Store," a fundraiser to benefit the EB Medical Research Foundation, in the Hollywood section of Los Angeles on Aug. 14, 2006.

Actress Courteney Coxand husband, actor David Arquette arrive at the premiere of Paramount Picture's "Barnyard" at the Cinerama Dome Theater on July 30, 2006, in Los Angeles.

Courteney Cox star in the comedy series "Friends," and her husband David Arquette enjoy the Governor's Ball after the 55th annual Primetime Emmy Awards Sunday, Sept. 21, 2003, in Los Angeles.

Courteney Cox, left, and David Arquette watch a monitor during taping of "Mix It Up," in this undated publicity photo. The couple were executive producers of the interior design show.

Courtney Cox Arquette David Arquette at the wedding of Cox's "Friends" co-star Jennifer Aniston to actor Brad Pitt on July 29, 2000. Pitt and Aniston divorced five years later.

David Arquette and Courteney Cox — GETTY IMAGES/Charley Gallay

David Arquette and actress Courteney Cox at the after party for the FX Network's premiere screening of "Dirt" at Republic on Dec. 9, 2006, in Los Angeles.

Actress Courteney Cox of the nominated series "Friends," arrives with her husband, actor David Arquette, to the 2002 Emmy awards ceremony in Los Angeles.