The first woman to fly across the Atlantic Ocean. (Credit: AP)
Aretha Franklin
Franklin is referred to as "The Queen of Soul." (Credit: Getty Images)
Audrey Hepburn
Hepburn was one of the most successful film actresses in the world. (Credit: AP)
Barbara Walters
Walters was the first female co-anchor of network evening news. (Credit: Getty Images)
Barbra Streisand
Streisand is one of the most successful entertainers in modern entertainment history, with more than 71.5 million albums shipped in the United States and 140 million albums sold worldwide. (Credit: Getty Images)
Betty White
White is the oldest person to guest-host Saturday Night Live, for which she also received a Primetime Emmy Award. (Credit: Getty Images)
Celine Dion
Dion is the only female artist to have two singles that have sold more than a million copies in the United Kingdom. (Credit: Ethan Miller/Getty Images)
Cher
Cher is the only artist to reach the number one on the Billboard charts in each of the previous six decades, and also holds this record for four and five decades. (Credit: Getty Images)
Danica Patrick
Danica Patrick is the first woman to win an Indy car race. (Credit: Getty Images)
Ella Fitzgerald
Fitzgerald is considered one of the greatest jazz singers of all time. (Credit: AP)
Hattie McDaniel
McDaniel was the first African-American to win an Academy Award. (Credit: AP)
Helen Keller
Keller was the first deafblind person to earn a Bachelor of Arts degree. (Credit: AP)
Hillary Clinton
Clinton was elected as a U.S. Senator in 2000, which made her the first female senator to represent the state of New York. (Credit: JIM WATSON/AFP/Getty Images)
J.K. Rowling
Rowling is a British author best known as the creator of the Harry Potter fantasy series. (Credit: Dave Hogan/Getty Images)
Judy Garland
Garland is best known for her role as Dorothy in "The Wizard of Oz." (Credit: AP)
Katie Couric
Couric is the first solo female anchor of a weekday evening news program on one of the three traditional U.S. broadcast networks. (Credit: Taylor Hill/Getty Images)
Lucille Ball
Ball was the star "I Love Lucy." (Credit: AFP/AFP/Getty Images)
Maria Shriver
Shriver is an American journalist and author of six best-selling books. (Credit: Cliff Owen-Pool/Getty Images)
Meryl Streep
Streep is widely regarded as one of the most talented and respected actresses of the modern era. (Credit: Getty Images)
Michelle Obama
Michelle Obama is the first African-American First Lady of the United States. (Credit: SAUL LOEB/AFP/Getty Images)
Mother Teresa
For over 45 years Mother Teresa ministered to the poor, sick, orphaned, and dying. (Credit: AP)
Nancy Pelosi
Pelosi was the first woman to hold the office and the highest-ranking female politician in American history. (Credit: Getty Images)
Nancy Reagan
Reagan has remained active in politics, particularly in support of stem-cell research. (Credit: KAREN BLEIER/AFP/Getty Images)
Oprah Winfrey
Winfrey was the first African American female television host. (Credit: Getty Images)
Princess Diana
Princess Diana was an international personality of the late 20th century as the first wife of Charles, Prince of Wales. (Credit: PATRICK RIVIERE/AFP/Getty Images)
Rosa Parks
Parks was an African-American civil rights activist. (Credit: AP)
Susan B. Anthony
The 19th century women’s movement’s most powerful organizer. (Credit: AP)
Susan Lucci
Lucci is best known for playing Erica Kane on the ABC television soap opera All My Children. (Credit: Getty Images)
Suze Orman
Orman is an American financial advisor and host of The Suze Orman Show on CNBC. (Credit: Getty Images)
Twiggy
At 16, Twiggy became the first prominent teenage model. (Credit: Getty Images)
Tyra Banks
Banks was the first African American woman on the covers of GQ and the Sports Illustrated Swimsuit Issue. (Credit: Getty Images)
Venus and Serena Williams
Venus is a seven-time Grand Slam title winner, and Serena is a thirteen-time Grand Slam title winner. (Credit: Getty Images)
Wendy Kopp
Kopp is the founder and President of Teach for America. (Credit: Stephen Lovekin/Getty Images)
Whitney Houston
Houston is the most awarded female artist of all time, according to Guinness World Records. (Credit: Getty Images)
Elizabeth Taylor
Taylor is considered one of the great actresses of Hollywood's golden age. (Credit: OLIVIER LABAN-MATTEI/AFP/Getty Images)