There is no shelter in place and the fire is no longer active, the Pasadena Fire Marshal said.
Kuraray America Eval confirmed there was a fire and explosion at their facility and said flames, emergency vehicles, odor and smoke may be noticeable to members of the community.
"We are coordinating with local officials, and working to resolve the issue as soon as possible," the company said in a statement.
Company officials said they believe a valve malfunctioned, triggering the explosion and fire.
Kuraray America Eval describes itself on its website as a global leader in specialty chemical, fiber and resin production.