2016 Billboard Music Awards highlights
Millennium Award recipient Britney Spears (C) performs a medley of songs at the 2016 Billboard Awards in Las Vegas, May 22, 2016.
Click through to see highlights from the show.
Stories on CBSNews.com: 2016 Billboard Music Awards: List of winners
Madonna, Stevie Wonder pay homage to Prince at Billboard Music Awards
Britney Spears
Millennium Award recipient Britney Spears performs a medley of songs at the 2016 Billboard Awards in Las Vegas, May 22, 2016.
Britney Spears
Millennium Award recipient Britney Spears performs a medley of songs at the 2016 Billboard Awards in Las Vegas, May 22, 2016.
Fifth Harmony
Fifth Harmony perform "Work From Home" at the 2016 Billboard Awards in Las Vegas, May 22, 2016.
Questlove
Questlove introduces Madonna's tribute to Prince at the 2016 Billboard Awards in Las Vegas, May 22, 2016.
Madonna
Madonna performs "Nothing Compares 2 U" during her tribute to Prince at the 2016 Billboard Awards in Las Vegas, May 22, 2016.
Madonna
Madonna performs "Nothing Compares 2 U" during her tribute to Prince at the 2016 Billboard Awards in Las Vegas, May 22, 2016.
Madonna
Stevie Wonder and Madonna perform "Purple Rain" during the tribute to Prince at the 2016 Billboard Awards in Las Vegas, May 22, 2016.
Pink
Pink Performs "Just Like Fire" at the 2016 Billboard Awards in Las Vegas, May 22, 2016.
Steven Tyler
Singer Steven Tyler presents the award for Top Artist to Adele, who was unable to attend, at the 2016 Billboard Awards in Las Vegas, May 22, 2016.
Ariana Grande
Ariana Grande performs "Dangerous Woman" at the 2016 Billboard Awards in Las Vegas, May 22, 2016.
Celine Dion
Billboard Icon Award recipient Celine Dion holds hands with the presenter, her son Rene Charles, as she accepts the award at the 2016 Billboard Awards in Las Vegas, May 22, 2016.
Celine Dion
Billboard Icon Award recipient Celine Dion kisses her son Rene Charles as he presents the award to her at the 2016 Billboard Awards in Las Vegas, May 22, 2016.
Rihanna
Rihanna accepts the Billboard Chart Achievement Award at the 2016 Billboard Awards in Las Vegas, May 22, 2016.
Rihanna
Rihanna bows after performing "Love On The Brain" at the 2016 Billboard Awards in Las Vegas, May 22, 2016.
Rihanna
Rihanna performs "Love On The Brain" at the 2016 Billboard Awards in Las Vegas, May 22, 2016.
Celine Dion
Celine Dion performs "The Show Must Go On" at the Billboard Music Awards at the T-Mobile Arena on Sunday, May 22, 2016, in Las Vegas.
The Go-Gos
Belinda Carlisle of The Go-Gos performs "We Got The Beat" at the 2016 Billboard Awards in Las Vegas, May 22, 2016.
Troye Sivan
Troye Sivan performs "Youth" at the 2016 Billboard Awards in Las Vegas, May 22, 2016.
The Weeknd
The Weeknd blows a kiss as he accepts the award for Top R&B Song for "The Hills" at the 2016 Billboard Awards in Las Vegas, May 22, 2016.
Kesha
Kesha gestures after she performed "It Ain't Me Babe" at the 2016 Billboard Awards in Las Vegas, May 22, 2016.
Kesha
Ben Folds, left, and Kesha perform "It Ain't Me Babe" at the Billboard Music Awards at the T-Mobile Arena on May 22, 2016 in Las Vegas.
Joe Jonas and Dnce
Joe Jonas and Dnce perform "Cake By The Ocean" at the 2016 Billboard Awards in Las Vegas, May 22, 2016.
Blake Shelton and Gwen Stefani
Blake Shelton and Gwen Stefani embrace after performing "Go Ahead And Break My Heart" at the 2016 Billboard Awards in Las Vegas, May 22, 2016.
Blake Shelton and Gwen Stefani
Blake Shelton and Gwen Stefani walk offstage hand in hand after performing "Go Ahead And Break My Heart" at the 2016 Billboard Awards in Las Vegas, May 22, 2016.
Demi Lovato
Singer Demi Lovato performs "Cool For The Summer" on stage at the 2016 Billboard Awards in Las Vegas, May 22, 2016.
Lukas Graham
Lukas Graham performs "7 Years" on stage at the 2016 Billboard Awards in Las Vegas, May 22, 2016.
Nick Jonas and Tove Lo
Nick Jonas performs "Close" with Tove Lo (L) at the 2016 Billboard Awards in Las Vegas, May 22, 2016.
Tove Lo
Tove Lo performs "Close" with Nick Jonas (not pictured) at the 2016 Billboard Awards in Las Vegas, May 22, 2016.
Justin Bieber
Justin Bieber accepts the award for Top Male Artist at the 2016 Billboard Awards in Las Vegas, May 22, 2016.
Justin Bieber
Justin Bieber performs a medley of songs at the 2016 Billboard Awards in Las Vegas, May 22, 2016.
Jessica Alba
Actress Jessica Alba presents the award for Top Male Artist at the 2016 Billboard Awards in Las Vegas, May 22, 2016.
Pink
Pink Performs "Just Like Fire" at the 2016 Billboard Awards in Las Vegas, May 22, 2016.
Thomas Rhett
Thomas Rhett accepts the award for Top Country Song for "Die A Happy Man" at the 2016 Billboard Awards in Las Vegas, May 22, 2016.
Mark Cuban and Betty Cantrell
Entrepreneur Mark Cuban and Miss America Betty Cantrell announce the winner for Top Country Song at the 2016 Billboard Awards in Las Vegas, May 22, 2016.
Shawn Mendes
Shawn Mendes performs "Stitches" at the 2016 Billboard Awards in Las Vegas, May 22, 2016.
Seal and Heidi Klum
Singer Seal and model Heidi Klum speak to a member of the audience during a commercial break at the 2016 Billboard Awards in Las Vegas, May 22, 2016.
Meghan Trainor
Meghan Trainor performs "No" at the 2016 Billboard Awards in Las Vegas, May 22, 2016.
Stories on CBSNews.com: 2016 Billboard Music Awards: List of winners
Madonna, Stevie Wonder pay homage to Prince at Billboard Music Awards